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PBHLTH252C

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Intervention Trial Design

School of Public HealthGraduatePBHLT - School of Public Health

Subject

PBHLTH

Course Number

252C

Course Level

Graduate

Course Title

Intervention Trial Design

Course Description

Students learn through pre-recorded lectures. There are graded student presentations of final course project to interpret and design clinical and population-level field trials in addition to a written midterm. Topics: formulation of a testable trial hypothesis; identification of appropriate study populations; blinding (including indices for assessment); randomization (including traditional and adaptive); sample size estimation; recruitment strategies; data collection systems; quality control and human subjects responsibilities; adverse effects monitoring; improving participant adherence; use of surrogate outcomes; preparation of a meta-analysis summarizing a group of trials.

Minimum

2

Maximum

2

Grading Basis

Default Letter Grade; S/U Option

Instructors

Colford

American Cultures Requirement

No

Reading and Composition Requirement

None of the Reading and Composition Requirement

Repeat Rules

Course is not repeatable for credit.

Student Learning Outcomes

At the completion of the course, students will be able to: 1) critique published Intervention Trials with respect to design and potential sources of bias: : 2) understand and apply basic principles to determine an appropriate sample size for a Trial; 3) identify whether appropriate steps have been taken to provide transparency in a published Trial; 4) be able to design a basic Intervention Trial in the student’s area of interest; 5) prepare a summary meta-analysis for a group of published Trials published on one topic of interest to the student.

Formats

Lecture, Discussion

Term

Fall and Spring

Duration (in weeks)

15

Minimum Hours

1

Maximum Hours

1

Lecture Mode of Instruction

Online

Minimum Hours

1

Maximum Hours

1

Discussion Mode of Instruction

In Person, Online

Outside Work Hours Min

4

Maximum Hours

4