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PBHLTH252C

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Intervention Trial Design

School of Public HealthGraduatePBHLT - School of Public Health

Subject

PBHLTH

Course Number

252C

Course Level

Graduate

Course Title

Intervention Trial Design

Course Description

Students learn through pre-recorded lectures. There are graded student presentations of final course project to interpret and design clinical and population-level field trials in addition to a written midterm. Topics: formulation of a testable trial hypothesis; identification of appropriate study populations; blinding (including indices for assessment); randomization (including traditional and adaptive); sample size estimation; recruitment strategies; data collection systems; quality control and human subjects responsibilities; adverse effects monitoring; improving participant adherence; use of surrogate outcomes; preparation of a meta-analysis summarizing a group of trials.

Minimum

2

Maximum

2

Grading Basis

Default Letter Grade; S/U Option

Instructors

Colford

American Cultures Requirement

No

Reading and Composition Requirement

None of the Reading and Composition Requirement
Prerequisite
Complete ALL of the following Courses:

Repeat Rules

Course is not repeatable for credit.

Student Learning Outcomes

At the completion of the course, students will be able to: 1) critique published Intervention Trials with respect to design and potential sources of bias: : 2) understand and apply basic principles to determine an appropriate sample size for a Trial; 3) identify whether appropriate steps have been taken to provide transparency in a published Trial; 4) be able to design a basic Intervention Trial in the student’s area of interest; 5) prepare a summary meta-analysis for a group of published Trials published on one topic of interest to the student.

Formats

Lecture, Discussion

Term

Fall and Spring

Duration (in weeks)

15

Minimum Hours

1

Maximum Hours

1

Lecture Mode of Instruction

Online

Minimum Hours

1

Maximum Hours

1

Discussion Mode of Instruction

In Person, Online

Outside Work Hours Min

4

Maximum Hours

4